is a pyridine derivative. It has fungicidal effects. Hydroxypyrone is a highly effective, non-toxic and non-irritating anti-dandruff agent that can be widely used in anti-dandruff shampoo, hair care lotion, conditioner and other washing and care cosmetics.
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1. The anti-dandruff and anti-itching effects are better than similar products.
2. Excellent solubility and compounding properties, no precipitation or stratification occurs when mixed with cosmetic raw materials.
3. The anti-dandruff mechanism is unique, with extremely low irritation, and will not cause hair loss or hair breakage. The safety is better than similar anti-dandruff and anti-itching products.
An HPLC method was developed and validated for the analysis of Piroctone olamine. The melting point was determined using the DSC Q2000 (TA Instruments, USA). The distribution coefficient (logD (O/PBS)) and partition coefficient (log P o/w) was determined in phosphate‐buffered saline (PBS) AND deionized (DI) water using the shake flask method. All experiments were performed at room temperature.
The solubility was determined experimentally by adding amount of active to a solvent. The samples were kept at 32 degree ± 1 degree for 48 h in a water bath. The stability of the compound was determined in a range of solvents by preparing solutions of 1 mg mL−1 in the relevant solvents. These solutions were kept and stirred throughout the experiment at 32 ± 1 degree , and aliquots were taken at 24, 48 and 96 h.
| 8.5~ 10.0 | 9.65 | |
| 130-136 | 133.1~ 133.8 | |
| Less than or equal to 0.20% | 0.16% | |
| >98.0% | 99.50% | |
| Less than or equal to 0.3% | 0.22% | |
| 20.0~21.0 | 20.78 | |
| Less than or equal to 50ppb | Less than or equal to 50ppb | |
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Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.
We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.
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3-7 days |
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Suitable for under 50kg. |
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7-15 days |
Suitable for more than 50kg. |
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15-60 days |
Suitable for more than 500kg. |
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